17 Thireou
نویسندگان
چکیده
The analysis of dynamic positron emission tomography (PET) studies provides clinically useful parametric information, but often requires complex and timeconsuming compartmental or non-compartmental techniques. Independent component analysis (ICA), a statistical method used for feature extraction and signal separation, is applied to dynamic PET studies to facilitate the initial interpretation and visual analysis of these large image sequences. ICA produces parametric images, where structures with different kinetic characteristics are assigned opposite values and readily discriminated, improving the identification of lesions and facilitating the posterior detailed kinetic analysis.
منابع مشابه
The environmental two-step.
An important stage in macromolecular crystallography is that of phase extension and refinement when initial phase estimates are available from isomorphous replacement or anomalous scattering or other methods. For this purpose, an alternative method called the twin variables (TwiV) method has been proposed. The algorithm is based on alternately transferring the phase information between the twin...
متن کاملA Survey of the Availability of Primary Bioinformatics Web Resources
The explosive growth of the bioinformatics field has led to a large amount of data and software applications publicly available as web resources. However, the lack of persistence of web references is a barrier to a comprehensive shared access. We conducted a study of the current availability and other features of primary bioinformatics web resources (such as software tools and databases). The m...
متن کاملAnalysis and interpretation of dynamic FDG PET oncological studies using data reduction techniques
BACKGROUND Dynamic positron emission tomography studies produce a large amount of image data, from which clinically useful parametric information can be extracted using tracer kinetic methods. Data reduction methods can facilitate the initial interpretation and visual analysis of these large image sequences and at the same time can preserve important information and allow for basic feature char...
متن کاملCrystTwiV: a webserver for automated phase extension and refinement in X-ray crystallography
An important stage in macromolecular crystallography is that of phase extension and refinement when initial phase estimates are available from isomorphous replacement or anomalous scattering or other methods. For this purpose, an alternative method called the twin variables (TwiV) method has been proposed. The algorithm is based on alternately transferring the phase information between the twin...
متن کاملHHT1 (MIM #187300), with a high incidence of gastrointestinal bleeding, pulmonary and cerebral arteriovenous malformations, and HHT2 (MIM #600376), with a high incidence of hepatic arteriovenous
About 80% of Rendu-Osler–Weber (ROW) patients carry mutations in endoglin (ENG) or activin receptor-like kinase1 (ACVRL1; ALK1) genes. In order to investigate the molecular mechanisms that govern the pathogenic effect of the mutations in ACVRL1, we have collected and analyzed the mutational effect of over 80 different predominant mutations, as well as their location, on the 3D molecular structu...
متن کامل